Description

2-Bromo-5-Iodobenzoic Acid Methyl Ester is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its versatility as a key intermediate in the construction of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and functionalized ligands for catalysis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the reactivity of both bromine and iodine substituents.
• Material Science: Serves as a building block for organic electronic materials, including organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for transition metal catalysis, such as palladium-catalyzed cross-coupling reactions.
• Chemical Biology: Useful for creating molecular probes and tags due to the orthogonal reactivity of its halogen atoms for further functionalization.
• Academic & Industrial R&D: A standard reagent for method development and exploring new synthetic pathways in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Bromo-5-Iodobenzoic Acid Methyl Ester
CAS No.	717880-58-5
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	Methyl 2-Bromo-5-iodobenzoate; Benzoic acid, 2-bromo-5-iodo-, methyl ester; 2-Bromo-5-iodobenzoic acid methyl ester; Methyl 5-iodo-2-bromobenzoate; 5-Iodo-2-bromobenzoic acid methyl ester; Methyl o-bromo-m-iodobenzoate
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodobenzoic Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.