Description

3-Bromo-5-Methoxypicolinonitrile is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and nitrile functional groups, makes it an indispensable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and industrial R&D teams in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging its halogenated heterocyclic core.
• Ligand & Catalyst Synthesis: Employed in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	3-Bromo-5-Methoxypicolinonitrile
CAS No.	717843-46-4
Molecular Formula	C7H5BrN2O
Molecular Weight	213.03 g/mol
Synonyms	5-Methoxy-3-bromopicolinonitrile; 3-Bromo-5-methoxypyridine-2-carbonitrile; 2-Cyano-3-bromo-5-methoxypyridine; 3-Bromo-5-methoxy-2-pyridinecarbonitrile; 717843-46-4; 3-Br-5-MeO-Picolinonitrile
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Methoxypicolinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.