Description

3-Bromo-4-Methylpicolinonitrile is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and nitrile functional groups on a methylated pyridine core, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine scaffold.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags used in biochemical and cellular studies.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Bromo-4-Methylpicolinonitrile
CAS No.	717843-45-3
Molecular Formula	C7H5BrN2
Molecular Weight	197.04 g/mol
Synonyms	3-Bromo-4-methylpyridine-2-carbonitrile; 4-Methyl-3-bromopicolinonitrile; 2-Cyano-3-bromo-4-methylpyridine; 3-Bromo-4-methyl-2-pyridinecarbonitrile; 3-Bromo-4-methyl-2-cyanopyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Methylpicolinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.