Description

5-Amino-4-Chloro-2-Fluoro-Benzoic Acid Methyl Ester is a high-purity, multi-functional aromatic building block of significant commercial and research interest. Its molecular structure, featuring strategically placed amino, chloro, and fluoro substituents, makes it a versatile intermediate for synthesizing complex molecules. This compound is primarily sought after by the pharmaceutical and agrochemical industries for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Development: Serves as a building block for creating specialized organic molecules used in electronic displays and lighting.
• Dye & Pigment Manufacturing: Employed in the synthesis of complex, high-performance dyes and pigments for industrial applications.
• Organic Synthesis & Chemical Research: A valuable reagent in academic and industrial R&D for constructing complex heterocycles and exploring novel chemical reactions.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	5-Amino-4-Chloro-2-Fluoro-Benzoic Acid Methyl Ester
CAS No.	716362-14-0
Molecular Formula	C8H6ClFNO2
Molecular Weight	217.59 g/mol
Synonyms	Methyl 5-Amino-4-Chloro-2-Fluorobenzoate; 4-Chloro-2-Fluoro-5-Aminobenzoic Acid Methyl Ester; Benzoic acid, 5-amino-4-chloro-2-fluoro-, methyl ester; 5-Amino-4-chloro-2-fluorobenzoic acid methyl ester; Methyl 5-amino-4-chloro-2-fluorobenzoate; 716362-14-0; 4-Chloro-2-fluoro-5-aminobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-Amino-4-Chloro-2-Fluoro-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high standards, including pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.