Description

2,8-Diazaspiro[4.5]Decan-1-One, 2-(Phenylmethyl)- is a high-value, nitrogen-containing spirocyclic compound with the CAS number 716324-44-6. This advanced pharmaceutical intermediate is crucial for the synthesis of complex molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and biotechnology sectors for the creation of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis: Serves as a precursor for the development of more complex spirocyclic and heterocyclic compounds in academic and industrial research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Bioconjugation Chemistry: Potential use in the development of targeted drug delivery systems and antibody-drug conjugates (ADCs) due to its functionalizable structure.

Basic Information

Product Name	2,8-Diazaspiro[4.5]Decan-1-One, 2-(Phenylmethyl)-
CAS No.	716324-44-6
Molecular Formula	C15H20N2O
Molecular Weight	244.33 g/mol
Synonyms	2-Benzyl-2,8-diazaspiro[4.5]decan-1-one; 2-Benzyl-1-oxa-2,8-diazaspiro[4.5]decane; 2-(Phenylmethyl)-2,8-diazaspiro[4.5]decan-1-one; 2,8-Diazaspiro[4.5]decan-1-one, 2-benzyl-; 716324-44-6; 2-Benzyl-1-oxa-2,8-diazaspiro[4.5]decane; Spirocyclic benzyl diazadecanone
EINECS	Contact for details

Quality Control

Our 2,8-Diazaspiro[4.5]Decan-1-One, 2-(Phenylmethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.