Description

(6-Bromo-3H-Imidazo[4,5-B]Pyridin-2-Yl)Methanamine is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure containing bromine and an amine functional group. This compound is of significant value for its role as a critical building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including kinase inhibitors and other small-molecule drugs. The compound's specific reactivity profile makes it essential for constructing targeted molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies.
• Kinase Inhibitor Development: Serves as a core scaffold or substituent in the research and production of potent and selective kinase inhibitors.
• Medicinal Chemistry & Drug Discovery: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to develop new drug candidates.
• Biochemical Research: Employed as a tool compound or labeled derivative in proteomics and molecular biology research to study enzyme mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical industry for custom synthesis projects.

Basic Information

Product Name	(6-Bromo-3H-Imidazo[4,5-B]Pyridin-2-Yl)Methanamine
CAS No.	713139-54-9
Molecular Formula	C7H7BrN4
Molecular Weight	227.06 g/mol
Synonyms	2-Aminomethyl-6-bromo-3H-imidazo[4,5-b]pyridine; 6-Bromo-2-(aminomethyl)-1H-imidazo[4,5-b]pyridine; 6-Bromo-3H-imidazo[4,5-b]pyridin-2-ylmethanamine; (6-Bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanamine; 6-Bromo-2-(aminomethyl)imidazo[4,5-b]pyridine; 713139-54-9; (6-Bromoimidazo[4,5-b]pyridin-2-yl)methanamine
EINECS	Contact for details

Quality Control

Our production of (6-Bromo-3H-Imidazo[4,5-B]Pyridin-2-Yl)Methanamine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D and scale-up. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.