Description

Methyl trans-3-Aminocyclohexanecarboxylate Hydrochloride, 97% is a high-purity chiral building block and intermediate of significant importance in synthetic organic chemistry. Its value lies in its defined stereochemistry and protected amine functionality, which are critical for constructing complex molecules with high enantiomeric purity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts and auxiliaries.
• Peptidomimetics & Bioactive Molecule Design: The cyclohexane scaffold and amino ester group are valuable for creating conformationally restricted peptide analogs and other bioactive compounds.
• Academic & Industrial R&D: A versatile building block for methodological development in organic synthesis and medicinal chemistry programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high stereochemical fidelity.

Basic Information

Product Name	Methyl trans-3-Aminocyclohexanecarboxylate Hydrochloride, 97%
CAS No.	712313-64-9
Molecular Formula	C8H16ClNO2
Molecular Weight	193.67 g/mol (Free base: 157.21 g/mol)
Synonyms	trans-Methyl 3-aminocyclohexanecarboxylate hydrochloride; Methyl (1R,3S)-3-aminocyclohexanecarboxylate hydrochloride (enantiomer); Methyl 3-aminocyclohexanecarboxylate HCl; 3-Aminocyclohexanecarboxylic acid methyl ester hydrochloride; trans-3-(Methoxycarbonyl)cyclohexylamine hydrochloride; Cyclohexanecarboxylic acid, 3-amino-, methyl ester, hydrochloride, trans-; (trans)-Methyl 3-aminocyclohexane-1-carboxylate hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl trans-3-Aminocyclohexanecarboxylate Hydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the specified 97% minimum purity and stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.