Description

3-Piperidinecarboxylic Acid, 1-Acetyl-, (3R)- (9Ci) is a high-purity, single-enantiomer chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, process development, and the synthesis of novel materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder drug candidates.
• Agrochemical Synthesis: Used in the preparation of enantiomerically pure active ingredients for advanced crop protection products.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & Industrial Research: A valuable tool compound for methodological studies in organic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals requiring specific stereochemical configurations.

Basic Information

Product Name	3-Piperidinecarboxylic Acid, 1-Acetyl-, (3R)- (9Ci)
CAS No.	712270-39-8
Molecular Formula	C8H13NO3
Molecular Weight	171.19 g/mol
Synonyms	(R)-1-Acetylpiperidine-3-carboxylic Acid; (3R)-1-Acetyl-3-piperidinecarboxylic Acid; (R)-N-Acetyl-nipecotic Acid; 1-Acetyl-(3R)-piperidine-3-carboxylic Acid; (R)-1-Acetyl-3-piperidinecarboxylic Acid; (R)-1-Acetylnipecotic Acid; (3R)-1-Acetylpiperidine-3-carboxylic Acid; 712270-39-8
EINECS	Contact for details

Quality Control

Our 3-Piperidinecarboxylic Acid, 1-Acetyl-, (3R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.