Description

7-Bromo-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one is a high-purity brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for medicinal chemistry research, enabling the development of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new drug candidates, particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical space.
• Chemical Biology Probe Synthesis: Employed in the construction of molecular probes for target identification and validation in biological systems.
• Custom Synthesis & Contract Manufacturing: Sourced by CDMOs for the production of proprietary compounds and advanced intermediates under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for methodological development in heterocyclic chemistry.

Basic Information

Product Name	7-Bromo-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one
CAS No.	709652-84-6
Molecular Formula	C7H6BrN3O
Molecular Weight	228.05 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-2-one; 7-Bromo-3,4-dihydro-1H-pyrido[2,3-b]pyrazin-2-one; 1,2,3,4-Tetrahydropyrido[2,3-b]pyrazin-2-one, 7-bromo-; 709652-84-6; 7-Bromo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-2-one; 7-Bromotetrahydropyrido[2,3-b]pyrazin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-3,4-dihydropyrido[2,3-b]pyrazin-2(1H)-one is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.