Description

2-Amino-5-Bromo-Nicotinonitrile is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both amino and nitrile functional groups adjacent to a bromine substituent, makes it a valuable scaffold for constructing complex heterocyclic systems. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, dyes, and photoactive compounds.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis Building Block: Provides a functionalized core for contract research organizations (CROs) and CDMOs performing bespoke synthesis.

Basic Information

Item	Details
Product Name	2-Amino-5-Bromo-Nicotinonitrile
CAS No.	709652-82-4
Molecular Formula	C6H4BrN3
Molecular Weight	198.02 g/mol
Synonyms	5-Bromo-2-aminonicotinonitrile; 2-Amino-5-bromopyridine-3-carbonitrile; 3-Cyano-5-bromopyridin-2-amine; 5-Bromo-2-amino-3-cyanopyridine; 709652-82-4; 2-Amino-5-bromo-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Bromo-Nicotinonitrile is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure it meets the high standards required for research and commercial synthesis. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.