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(11β)-17-(Acetyloxy)-11-[4-(Dimethylamino)Phenyl]-3-Hydroxy-19-Norpregna-1,3,5(10)-Trien-20-One CAS NO 709615-25-8
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CAS No.:709615-25-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(11β)-17-(Acetyloxy)-11-[4-(Dimethylamino)Phenyl]-3-Hydroxy-19-Norpregna-1,3,5(10)-Trien-20-One is a high-purity, synthetic steroid derivative with a complex molecular architecture. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key intermediate or reference standard for novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing steroidal drugs, hormone modulators, and other bioactive molecules.
Application
- Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of novel steroidal drug candidates targeting various endocrine pathways.
- Reference Standard: Used as a high-purity analytical standard in method development and validation for quality control (QC) and research assays.
- Biochemical Research: Employed in in-vitro studies to investigate steroid receptor binding affinity, enzyme inhibition, and cellular signaling mechanisms.
- Process Chemistry Development: Acts as a model compound for optimizing synthetic routes, scaling up production, and developing purification protocols for complex steroids.
- Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry, organic synthesis, and steroid biology.
Basic Information
| Product Name | (11β)-17-(Acetyloxy)-11-[4-(Dimethylamino)Phenyl]-3-Hydroxy-19-Norpregna-1,3,5(10)-Trien-20-One |
| CAS No. | 709615-25-8 |
| Molecular Formula | C29H35NO4 |
| Molecular Weight | 461.60 g/mol |
| Synonyms | 11β-(4-Dimethylaminophenyl)-17α-acetoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-one; 11β-[4-(Dimethylamino)phenyl]-17α-acetoxy-19-nor-17α-pregna-1,3,5(10)-trien-20-one; 17-Acetoxy-11β-[4-(dimethylamino)phenyl]-19-norpregna-1,3,5(10)-trien-20-one; 11β-(4-Dimethylaminophenyl)estradiol 17-acetate derivative; 709615-25-8 (CAS Name); 19-Norpregna-1,3,5(10)-trien-20-one, 17-(acetyloxy)-11-[4-(dimethylamino)phenyl]-3-hydroxy-, (11β)- |
| EINECS | Contact for details |
Quality Control
Every batch of our (11β)-17-(Acetyloxy)-11-[4-(Dimethylamino)Phenyl]-3-Hydroxy-19-Norpregna-1,3,5(10)-Trien-20-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency suitable for research and development applications. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and identification are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Retention time matches reference standard |
| Assay (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% Any single impurity ≤ 1.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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