Description

1H-Pyrrole,1-[(Trimethylsilyl)ethynyl]-(9CI) is a specialized organosilicon building block featuring a pyrrole core functionalized with a trimethylsilyl-protected acetylene group. This compound matters for its role as a versatile synthon in advanced organic synthesis, enabling the construction of complex heterocyclic and conjugated molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications in medicinal chemistry and functional material design.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products.
• Material Science Research: Employed in the creation of advanced organic electronic materials, such as organic semiconductors and conductive polymers.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands used in transition metal catalysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological systems and enzyme functions.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new synthetic pathways in heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrrole,1-[(Trimethylsilyl)ethynyl]-(9CI)
CAS No.	709016-49-9
Molecular Formula	C9H13NSi
Molecular Weight	163.29 g/mol
Synonyms	1-[(Trimethylsilyl)ethynyl]-1H-pyrrole; 1-(2-Trimethylsilylethynyl)pyrrole; 1-Ethynyl-1H-pyrrole, 1-(trimethylsilyl)-; 1H-Pyrrole, 1-[(trimethylsilyl)ethynyl]-; N-(Trimethylsilylethynyl)pyrrole; Pyrrole, 1-[(trimethylsilyl)ethynyl]-; TMS-ethynylpyrrole
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole,1-[(Trimethylsilyl)ethynyl]-(9CI) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is sensitive to strong bases and should be kept away from such materials. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.