Description

8-(5-Bromopyridin-2-Yl)-1,4-Dioxaspiro[4.5]Decan-8-Ol is a high-value brominated pyridine derivative and a key spirocyclic building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, offering a unique structural motif that is difficult to access through other routes. Pharmaceutical, agrochemical, and advanced material researchers need this chemical for constructing novel active ingredients and functional materials with specific properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Academic & R&D: A valuable reagent for methodological development and exploring new chemical spaces in university and corporate research laboratories.

Basic Information

Product Name	8-(5-Bromopyridin-2-Yl)-1,4-Dioxaspiro[4.5]Decan-8-Ol
CAS No.	708274-37-7
Molecular Formula	C14H16BrNO3
Molecular Weight	326.19 g/mol
Synonyms	8-(5-Bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decan-8-ol; 1,4-Dioxaspiro[4.5]decan-8-ol, 8-(5-bromo-2-pyridinyl)-; 5-Bromo-2-(8-hydroxy-1,4-dioxaspiro[4.5]decan-8-yl)pyridine; 8-Hydroxy-8-(5-bromopyridin-2-yl)-1,4-dioxaspiro[4.5]decane; Bromopyridine Spiroketal Intermediate
EINECS	Contact for details

Quality Control

Our 8-(5-Bromopyridin-2-Yl)-1,4-Dioxaspiro[4.5]Decan-8-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.