Description

8-(6-Methoxypyridin-3-Yl)-1,4-Dioxaspiro[4.5]Decan-8-Ol is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and pyridine-based molecular architecture. This compound is of critical importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated chemical scaffolds. It is primarily needed by research institutions, custom synthesis organizations, and pharmaceutical companies engaged in the development of new drugs, agrochemicals, and other fine chemical products.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex spirocyclic and fused-ring systems in medicinal chemistry.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Investigated as a monomer or additive for creating novel polymers with specific optical or electronic properties.

Basic Information

Product Name	8-(6-Methoxypyridin-3-Yl)-1,4-Dioxaspiro[4.5]Decan-8-Ol
CAS No.	708273-56-7
Molecular Formula	C₁₇H₂₃NO₄
Molecular Weight	305.37 g/mol
Synonyms	8-(6-Methoxy-3-pyridinyl)-1,4-dioxaspiro[4.5]decan-8-ol; 1,4-Dioxaspiro[4.5]decan-8-ol, 8-(6-methoxy-3-pyridinyl)-; 8-(6-Methoxypyridin-3-yl)-1,4-dioxaspiro[4.5]decan-8-ol; 708273-56-7; 8-(6-Methoxy-3-pyridyl)-1,4-dioxaspiro[4.5]decan-8-ol; 8-(6-Methoxypyridin-3-yl)-1,4-dioxaspiro[4.5]decan-8-ol (CAS 708273-56-7); 8-(6-Methoxy-pyridin-3-yl)-1,4-dioxa-spiro[4.5]decan-8-ol
EINECS	Contact for details

Quality Control

Our production of 8-(6-Methoxypyridin-3-Yl)-1,4-Dioxaspiro[4.5]Decan-8-Ol adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.