Description

5-Fluoro-3H-Spiro[Isobenzofuran-1,4'-Piperidin]-3-One is a high-value spirocyclic organic compound featuring a fused isobenzofuran and piperidine structure with a fluorine substituent. This molecule serves as a critical pharmaceutical intermediate and advanced building block in modern organic synthesis, enabling the development of novel bioactive molecules. It is primarily sought by research institutions and chemical manufacturers in the pharmaceutical and agrochemical sectors for the development of new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential central nervous system (CNS) active compounds, receptor modulators, and enzyme inhibitors.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new therapeutic targets.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides with enhanced activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring complex, fluorinated spirocyclic architectures.

Basic Information

Product Name	5-Fluoro-3H-Spiro[Isobenzofuran-1,4'-Piperidin]-3-One
CAS No.	707541-47-7
Molecular Formula	C13H14FNO2
Molecular Weight	235.26 g/mol
Synonyms	5-Fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one; 5-Fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-3-one; 707541-47-7; 5-Fluoro-spiro[isobenzofuran-1(3H),4'-piperidin]-3-one; Spiro[isobenzofuran-1(3H),4'-piperidine]-3-one, 5-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-3H-Spiro[Isobenzofuran-1,4'-Piperidin]-3-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.