Description

trans-9-tert-Butyl-3-[4-(Trifluoromethoxy)Phenyl]-1,3-Diazaspiro[5.5]Undecan-2-One is a high-value, complex spirocyclic organic compound featuring a trifluoromethoxy phenyl group, making it a versatile and potent intermediate for advanced chemical synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structural motifs can impart desirable biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors engaged in drug discovery and the synthesis of high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Research: Used as a building block for developing new generation pesticides and herbicides, leveraging the trifluoromethoxy group for enhanced efficacy.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a scaffold for designing enzyme inhibitors.
• Material Science: Potential intermediate for creating specialty polymers or liquid crystals due to its rigid spirocyclic core.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	trans-9-tert-Butyl-3-[4-(Trifluoromethoxy)Phenyl]-1,3-Diazaspiro[5.5]Undecan-2-One
CAS No.	706813-26-5
Molecular Formula	C22H31F3N2O2
Molecular Weight	412.49 g/mol
Synonyms	trans-9-tert-Butyl-3-[4-(trifluoromethoxy)phenyl]-1,3-diazaspiro[5.5]undecan-2-one; 1,3-Diazaspiro[5.5]undecan-2-one, 9-(1,1-dimethylethyl)-3-[4-(trifluoromethoxy)phenyl]-, trans-; 9-tert-Butyl-3-(4-trifluoromethoxyphenyl)-1,3-diazaspiro[5.5]undecan-2-one (trans); CAS 706813-26-5; Spirocyclic trifluoromethoxy phenyl compound; TBDU-2-One derivative
EINECS	Contact for details

Quality Control

Our trans-9-tert-Butyl-3-[4-(Trifluoromethoxy)Phenyl]-1,3-Diazaspiro[5.5]Undecan-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, related substances, and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.