Description

Methyl 2-Bromo-5-(Difluoromethoxy)Benzoate is a high-purity, advanced pharmaceutical intermediate characterized by its bromine and difluoromethoxy functional groups. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry where its structure serves as a key building block for active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the difluoromethoxy group for enhanced biological activity and stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic materials.
• Chemical Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex aromatic systems for various R&D applications.

Basic Information

Product Name	Methyl 2-Bromo-5-(Difluoromethoxy)Benzoate
CAS No.	705279-03-4
Molecular Formula	C9H7BrF2O3
Molecular Weight	281.05 g/mol
Synonyms	Benzoic acid, 2-bromo-5-(difluoromethoxy)-, methyl ester; Methyl 2-bromo-5-(difluoromethoxy)benzoate; 2-Bromo-5-(difluoromethoxy)benzoic acid methyl ester; Methyl 2-bromo-5-difluoromethoxybenzoate; 705279-03-4; Methyl o-bromo-α,α-difluoroanisole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-5-(Difluoromethoxy)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are available for every shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.