Description

4,6-Dibromo-1H-Indole-2-Carboxylic Acid Ethyl Ester is a high-purity, multi-functional brominated indole derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block for complex organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Used in the synthesis of organic semiconductors, conductive polymers, and advanced organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Versatile reagent for Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions to create complex molecular architectures.
• Biochemical Probe Development: Serves as a core structure for creating fluorescent dyes or molecular probes for biological imaging and diagnostics.
• Academic & Industrial R&D: Essential for method development and exploratory chemistry in university and corporate research laboratories.

Basic Information

Product Name	4,6-Dibromo-1H-Indole-2-Carboxylic Acid Ethyl Ester
CAS No.	704909-87-5
Molecular Formula	C11H9Br2NO2
Molecular Weight	347.00 g/mol
Synonyms	Ethyl 4,6-Dibromo-1H-indole-2-carboxylate; 4,6-Dibromoindole-2-carboxylic Acid Ethyl Ester; 1H-Indole-2-carboxylic acid, 4,6-dibromo-, ethyl ester; 4,6-Dibromo-1H-indole-2-carboxylic acid ethyl ester; Ethyl 4,6-dibromoindole-2-carboxylate; DBICE; 4,6-DBIE
EINECS	Contact for details

Quality Control

Our 4,6-Dibromo-1H-Indole-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.