Description

4-Piperidinecarboxylic Acid, Phenylmethyl Ester, Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its value lies in its role as a versatile precursor for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex piperidine-based structures. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting the central nervous system (CNS), cardiovascular diseases, and other therapeutic areas.
• API Synthesis: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) that incorporate the piperidine pharmacophore.
• Agrochemical Research: Used in the research and development of new pesticides and herbicides, where its structural motif can contribute to biological activity.
• Chemical Biology & Medicinal Chemistry: Employed in library synthesis for high-throughput screening and structure-activity relationship (SAR) studies to identify new lead compounds.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis organizations (CSOs) and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	4-Piperidinecarboxylic Acid, Phenylmethyl Ester, Hydrochloride
CAS No.	704879-64-1
Molecular Formula	C13H17NO2 • HCl
Molecular Weight	255.74 g/mol
Synonyms	Benzyl 4-piperidinecarboxylate hydrochloride; Benzyl piperidine-4-carboxylate hydrochloride; 4-Carbobenzoxypiperidine hydrochloride; 1-Benzyloxycarbonyl-4-piperidinecarboxylic acid hydrochloride (incorrect but common); 1-Cbz-4-piperidinecarboxylic acid hydrochloride; Cbz-Pip-OH • HCl; 4-Piperidinecarboxylic acid, benzyl ester, hydrochloride; Z-Piperidine-4-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Piperidinecarboxylic Acid, Phenylmethyl Ester, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and tests for residual solvents and specific impurities to ensure it meets the stringent requirements for pharmaceutical R&D and production. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.