Description

Ethyl 2-Nitro-4-(Trifluoromethyl)Benzoate is a specialized aromatic ester building block featuring both nitro and trifluoromethyl functional groups, offering unique reactivity and physicochemical properties for advanced synthesis. This compound is valued for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for research chemists and process development scientists working on active ingredients, functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring the trifluoromethyl moiety for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the nitro and trifluoromethyl groups contribute to biological activity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions, reduction chemistry, and as a substrate for developing new synthetic methodologies in academic and industrial R&D.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex dyes and pigments, leveraging its aromatic nitro functionality.

Basic Information

Product Name	Ethyl 2-Nitro-4-(Trifluoromethyl)Benzoate
CAS No.	702673-02-7
Molecular Formula	C10H8F3NO4
Molecular Weight	263.17 g/mol
Synonyms	Ethyl 2-Nitro-α,α,α-trifluoro-p-toluate; Benzoic acid, 2-nitro-4-(trifluoromethyl)-, ethyl ester; 2-Nitro-4-(trifluoromethyl)benzoic acid ethyl ester; Ethyl 2-nitro-4-trifluoromethylbenzoate; Ethyl o-nitro-α,α,α-trifluoro-p-toluate; Ethyl 2-nitro-α,α,α-trifluoro-4-methylbenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Nitro-4-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.