Description

Proline, 3,3-Dimethyl-, Methyl Ester (9Ci) is a specialized proline derivative, a high-purity building block designed for advanced chemical synthesis. This compound is valued for its role in modifying peptide backbones and creating novel molecular architectures with enhanced properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and custom synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel peptide-based drugs and protease inhibitors.
• Agrochemical Research: Used in the development of new active ingredients and plant growth regulators.
• Peptide Chemistry: Employed to introduce sterically hindered, dimethyl-substituted proline motifs into peptides to study conformation-activity relationships.
• Organic Synthesis: Serves as a chiral synthon and precursor for complex natural product synthesis and catalyst development.
• Bioconjugation: Potential use in creating linkers and modifying biomolecules for diagnostic or therapeutic applications.

Basic Information

Product Name	Proline, 3,3-Dimethyl-, Methyl Ester (9Ci)
CAS No.	701197-44-6
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	Methyl 3,3-dimethylprolinate; 3,3-Dimethylproline methyl ester; L-Proline, 3,3-dimethyl-, methyl ester (9CI); Methyl (2S)-3,3-dimethylpyrrolidine-2-carboxylate; 3,3-Dimethyl-L-proline methyl ester; Proline methyl ester, 3,3-dimethyl-; (S)-Methyl 3,3-dimethylpyrrolidine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Proline, 3,3-Dimethyl-, Methyl Ester (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR, and MS for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is compatible with strong acids and organic solvents but should be stored separately from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.