Description

2H-Pyrido[1,2-A]Pyrimidine-7,8,9-Triol, Octahydro-7-(Hydroxymethyl)-, (7R,8R,9S,9Ar)- (9Ci) is a complex, stereochemically defined heterocyclic compound with significant potential in advanced organic synthesis and pharmaceutical research. Its unique polyhydroxylated pyridopyrimidine scaffold makes it a valuable chiral building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This high-purity intermediate is primarily targeted at research institutions and pharmaceutical R&D departments engaged in medicinal chemistry, process development, and the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) or anti-infective drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Serves as a critical intermediate for optimizing synthetic routes and scaling up the production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Utilized as a starting material or reagent in stereoselective synthesis due to its defined (7R,8R,9S,9Ar) configuration.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a complex, polyfunctional heterocyclic structure.
• Academic Research: Used in universities and research institutes for studies in organic synthesis methodology and the exploration of new chemical entities.

Basic Information

Item	Details
Product Name	2H-Pyrido[1,2-A]Pyrimidine-7,8,9-Triol, Octahydro-7-(Hydroxymethyl)-, (7R,8R,9S,9Ar)- (9Ci)
CAS No.	700372-13-0
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	(7R,8R,9S,9aR)-Octahydro-7-(hydroxymethyl)-2H-pyrido[1,2-a]pyrimidine-7,8,9-triol; (7R,8R,9S,9aR)-7-(Hydroxymethyl)octahydro-2H-pyrido[1,2-a]pyrimidine-7,8,9-triol; 700372-13-0; Octahydro-7-(hydroxymethyl)-2H-pyrido[1,2-a]pyrimidine-7,8,9-triol, (7R,8R,9S,9aR)-; A stereoisomer of a polyhydroxylated pyridopyrimidine.
EINECS	Contact for details

Quality Control

Our production of this advanced chemical intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. Quality is verified through comprehensive analytical techniques including HPLC, chiral analysis, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.