Description

(R)-Amino-Cyclopropyl-Acetic Acid Methyl Ester is a high-purity chiral building block essential for the synthesis of complex pharmaceutical intermediates. Its cyclopropyl and ester functionalities make it a valuable precursor for creating novel active pharmaceutical ingredients (APIs) with constrained geometries. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and crop protection products.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with specific stereochemical requirements for enhanced efficacy.
• Asymmetric Catalysis Research: Used as a substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts.
• Peptidomimetics: Serves as a constrained amino acid analog in the design and synthesis of peptide-like molecules for drug discovery.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological mechanisms.
• Custom Synthesis: Starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	(R)-Amino-Cyclopropyl-Acetic Acid Methyl Ester
CAS No.	700342-85-4
Molecular Formula	C₆H₁₁NO₂
Molecular Weight	129.16 g/mol
Synonyms	(R)-1-Aminocyclopropanecarboxylic acid methyl ester; Methyl (R)-1-aminocyclopropanecarboxylate; (R)-Methyl 1-aminocyclopropanecarboxylate; (R)-ACMP methyl ester; (R)-1-Amino-1-cyclopropanecarboxylic acid methyl ester; (R)-Methyl ACC; (R)-Cyclopropylglycine methyl ester
EINECS	Contact for details

Quality Control

Our (R)-Amino-Cyclopropyl-Acetic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.