Description

n-Palmitoyl L-Serine Methyl Ester is a synthetic lipoamino acid derivative, specifically the methyl ester of the N-palmitoylated form of the amino acid L-serine. This compound is a key intermediate and building block in the synthesis of more complex bioactive molecules, particularly in the development of advanced cosmetic and pharmaceutical actives. It is primarily sought after by R&D and production teams in the personal care, cosmetic, and fine chemical industries for its role in creating skin-identical ceramide analogs and other lipid-based formulations.

Application

• Cosmetic & Skincare Actives: A crucial synthetic precursor for the production of pseudoceramides and other skin barrier lipid analogs used in moisturizers, anti-aging, and repair formulations.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting lipid metabolism or requiring specific membrane permeability.
• Biochemical Research: Used as a standard or reagent in studies involving sphingolipid metabolism, cell signaling pathways, and membrane biophysics.
• Hair Care Products: Incorporated into conditioning agents and treatments designed to repair and strengthen hair fibers by mimicking natural lipid structures.
• Liposome & Nanocarrier Formulation: Employed in the design and synthesis of novel lipid components for advanced drug delivery systems.

Basic Information

Product Name	n-Palmitoyl L-Serine Methyl Ester
CAS No.	79876-27-0
Molecular Formula	C20H39NO4
Molecular Weight	357.53 g/mol
Synonyms	L-Serine, N-(1-oxohexadecyl)-, methyl ester; Methyl N-palmitoyl-L-serinate; Palmitoyl-L-serine methyl ester; N-Hexadecanoyl-L-serine methyl ester; (2S)-2-(Hexadecanoylamino)-3-hydroxypropanoic acid methyl ester; Methyl (2S)-2-(palmitoylamino)-3-hydroxypropanoate; L-Serine methyl ester, N-palmitoyl-; Ceramide precursor SP
EINECS	Contact for details

Quality Control

Our n-Palmitoyl L-Serine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for cosmetic and research applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Melting Point	Approx. 95 - 100 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.