Description

Ethanethioamide, 2,2,2-Trifluoro-N,n-Dimethyl- is a specialized organofluorine compound featuring a thioamide functional group, making it a valuable synthon in advanced chemical synthesis. This compound is particularly significant for its role in introducing the trifluoromethyl group and sulfur-containing motifs into target molecules, which are key structural features in modern pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring trifluoromethylated or thioamide pharmacophores to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl group confers improved activity and environmental persistence.
• Material Science Research: Serves as a precursor for novel polymers, ligands, or surface modifiers, leveraging its unique electronic properties imparted by the fluorine and sulfur atoms.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories as a versatile reagent for constructing complex heterocycles or for use in nucleophilic substitution and condensation reactions.
• Ligand and Catalyst Development: Useful in the design of new ligands for transition metal catalysis, where the thioamide group can act as a coordinating site.

Basic Information

Item	Details
Product Name	Ethanethioamide, 2,2,2-Trifluoro-N,n-Dimethyl-
CAS No.	79770-08-4
Molecular Formula	C4H6F3NS
Molecular Weight	157.16 g/mol
Synonyms	2,2,2-Trifluoro-N,N-dimethylthioacetamide; N,N-Dimethyl-2,2,2-trifluorothioacetamide; 2,2,2-Trifluoro-N,N-dimethylthioacetamide; Trifluoro-N,N-dimethylthioacetamide; TFDMTA; Thioacetamide, 2,2,2-trifluoro-N,N-dimethyl-; Ethanethioamide, 2,2,2-trifluoro-N,N-dimethyl-
EINECS	Contact for details

Quality Control

Our Ethanethioamide, 2,2,2-Trifluoro-N,n-Dimethyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.