Description

4,4,5,5,6,6,6-Heptafluoro-2-Iodohex-2-En-1-Ol is a highly fluorinated iodoalkenol building block, valued for its unique combination of a reactive vinyl iodide moiety and a terminal alcohol group within a perfluoroalkyl chain. This compound is critical for introducing lipophilic, electron-withdrawing fluorinated segments into target molecules via cross-coupling reactions. It is primarily sought by researchers and process chemists in the pharmaceutical and advanced materials sectors for the synthesis of novel bioactive compounds and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas, leveraging the metabolic stability imparted by the fluorine atoms.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides where the fluorinated chain enhances bioavailability and environmental persistence.
• Material Science: Serves as a monomer or modifier for creating fluorinated polymers, coatings, and surfactants with enhanced oil- and water-repellency, and chemical resistance.
• Liquid Crystal & OLED Materials: Incorporated into the molecular structure of advanced electronic display materials to tune dielectric properties and improve performance.
• Cross-Coupling Reactions: The vinyl iodide group is highly reactive in palladium-catalyzed couplings (e.g., Suzuki, Heck, Sonogashira) for carbon-carbon bond formation.
• Radiotracer & Diagnostic Agent Precursor: The iodine atom can be a site for radioiodination, making it a potential precursor for PET imaging agents.

Basic Information

Product Name	4,4,5,5,6,6,6-Heptafluoro-2-Iodohex-2-En-1-Ol
CAS No.	1422-42-0
Molecular Formula	C6H4F7IO
Molecular Weight	340.00 g/mol
Synonyms	2-Iodo-4,4,5,5,6,6,6-heptafluorohex-2-en-1-ol; 4,4,5,5,6,6,6-Heptafluoro-2-iodo-2-hexen-1-ol; Heptafluoro-2-iodohex-2-en-1-ol; 1-Hydroxy-4,4,5,5,6,6,6-heptafluoro-2-iodo-2-hexene; (E/Z)-4,4,5,5,6,6,6-Heptafluoro-2-iodohex-2-en-1-ol; HFAI; Perfluoroalkyl Vinyl Iodide Alcohol
EINECS	Contact for details

Quality Control

Our 4,4,5,5,6,6,6-Heptafluoro-2-Iodohex-2-En-1-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F), HPLC, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to light and potential reactivity with strong acids, the container should be kept in the original packaging until use. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Ratio (E/Z) (GC or HPLC)	Reported on COA
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.