Description

2,2,2-Trifluoroethanethiol is a specialized organosulfur compound characterized by its trifluoromethyl group and reactive thiol functionality. This unique structure makes it a valuable building block for introducing the trifluoroethylthio moiety into target molecules, enhancing properties like lipophilicity and metabolic stability. It is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in synthesis and chemical modification.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for incorporating fluorine to modulate bioavailability and binding affinity.
• Agrochemical Synthesis: Serves as a key precursor in creating novel herbicides, fungicides, and insecticides where the CF3S- group contributes to biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Surface Modification Agent: Used to functionalize materials and surfaces, imparting specific chemical properties through thiol-based chemistry.
• Chemical Research & Development: A versatile reagent in organic synthesis for constructing C-S bonds in fluorinated compounds.

Basic Information

Product Name	2,2,2-Trifluoroethanethiol
CAS No.	1544-53-2
Molecular Formula	C2H3F3S
Molecular Weight	116.10 g/mol
Synonyms	2,2,2-Trifluoroethyl Mercaptan; Trifluoroethanethiol; Trifluoroethylthiol; α,α,α-Trifluoroethanethiol; 2,2,2-Trifluoro-1-ethanethiol; Perfluoroethanethiol; F3CCH2SH; TFET
EINECS	216-284-9

Quality Control

Our 2,2,2-Trifluoroethanethiol is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat, sparks, and open flames. Due to its highly volatile and light-sensitive nature, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.