Description

tert-Butyl n-(Benzyloxy)Carbamate is a versatile carbamate derivative and a key protected intermediate in organic synthesis. Its primary value lies in its role as a protecting group for amines, enabling selective reactions in complex multi-step syntheses. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly for introducing and later deprotecting amine functionalities.
• Peptide Synthesis: Used as a protecting reagent for amino groups during solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Agrochemical Research: Serves as a key intermediate in the development of novel herbicides, insecticides, and fungicides that require amine protection strategies.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for the preparation of various carbamates, ureas, and other nitrogen-containing compounds.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, dyes, and functional materials where controlled amine reactivity is required.

Basic Information

Product Name	tert-Butyl n-(Benzyloxy)Carbamate
CAS No.	79722-21-7
Molecular Formula	C₁₂H₁₇NO₃
Molecular Weight	223.27 g/mol
Synonyms	Boc-OBn; tert-Butyl benzyloxycarbamate; N-(Benzyloxycarbonyloxy)succinimide, tert-Butyl ester; Carbamic acid, N-(benzyloxy)-, 1,1-dimethylethyl ester; Boc-ON; (Benzyloxy)carbamic acid tert-butyl ester; N-(tert-Butoxycarbonyloxy)benzamide (common misnomer); Boc benzyl carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(Benzyloxy)Carbamate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and loss on drying for moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	78°C - 82°C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.