Description

Pyridine, 3-Chloro-2,4-Bis(Trimethylsilyl)- (9Ci) is a specialized organosilicon derivative of pyridine, designed for advanced synthetic applications. This compound is valued for its dual trimethylsilyl (TMS) groups, which provide enhanced steric protection and reactivity control in sensitive chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing halogenated pyridine motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the chloropyridine core is essential for bioactivity.
• Organometallic Catalyst Ligand: Functions as a precursor or ligand in transition metal catalysis due to the electron-donating and steric properties of the TMS groups.
• Material Science Research: Employed in the synthesis of silicon-containing polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: Acts as a substrate or directing agent in palladium-catalyzed cross-coupling reactions like Suzuki or Stille couplings.
• Protecting Group Chemistry: The TMS groups can be utilized as temporary protecting groups for sensitive functional groups in multi-step synthesis.

Basic Information

Product Name	Pyridine, 3-Chloro-2,4-Bis(Trimethylsilyl)- (9Ci)
CAS No.	79698-59-2
Molecular Formula	C11H20ClNSi2
Molecular Weight	261.91 g/mol
Synonyms	3-Chloro-2,4-bis(trimethylsilyl)pyridine; 2,4-Bis(trimethylsilyl)-3-chloropyridine; 3-Chloro-2,4-di(trimethylsilyl)pyridine; Pyridine, 3-chloro-2,4-bis(trimethylsilyl)-; 79698-59-2; 3-Chloro-2,4-bis(trimethylsilyl)pyridin; 3-Chloro-2,4-di-TMS-pyridine
EINECS	Contact for details

Quality Control

Our production of Pyridine, 3-Chloro-2,4-Bis(Trimethylsilyl)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.