Description

2,3-Dibromo-5-(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethyl substituents, makes it an indispensable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used to construct advanced pyridine-based herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated ring.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized nitrogen-containing ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Building block for organic electronic materials, such as electron-transport layers in OLEDs and components of liquid crystals, due to its electron-deficient aromatic system.
• Fluorine Chemistry: The trifluoromethyl group makes it a valuable synthon for introducing fluorine motifs, which are crucial for modulating lipophilicity and metabolic stability in drug discovery.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	2,3-Dibromo-5-(Trifluoromethyl)Pyridine
CAS No.	79623-38-4
Molecular Formula	C6H2Br2F3N
Molecular Weight	313.89 g/mol
Synonyms	5-(Trifluoromethyl)-2,3-dibromopyridine; 2,3-Dibromo-5-(trifluoromethyl)pyridine; 2,3-Dibromo-5-trifluoromethylpyridine; Pyridine, 2,3-dibromo-5-(trifluoromethyl)-; 79623-38-4; AI3-52362; CTK8G7225; NSC 405124; ZINC000000899509
EINECS	Contact for details

Quality Control

Every batch of 2,3-Dibromo-5-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. Our standard quality commitment includes HPLC purity verification, identity confirmation by FT-IR and NMR, and stringent control of residual solvents and heavy metals. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support customer audits and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if frequent access is required. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	72 - 76 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.