Description

L-Allo-Threoninemethylester is a specialized, non-proteinogenic amino acid derivative, a stereoisomer of threonine methyl ester, with the CAS number 79617-28-0. This high-purity chiral building block is critical for the synthesis of complex peptides and pharmaceutical intermediates where precise stereochemistry is required. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and advanced biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of active pharmaceutical ingredients (APIs), particularly for antibiotics, enzyme inhibitors, and other bioactive molecules.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce the unique allo-threonine moiety, influencing peptide conformation and biological activity.
• Biochemical Research: Serves as a standard or reagent in metabolic studies, enzyme-substrate interaction research, and the development of diagnostic assays.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in stereoselective organic synthesis to construct complex molecular architectures.
• Proteomics & Molecular Biology: Utilized in the design and synthesis of modified peptides for studying protein structure, function, and protein-protein interactions.

Basic Information

Product Name	L-Allo-Threoninemethylester
CAS No.	79617-28-0
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	L-allo-Threonine methyl ester; (2S,3S)-2-Amino-3-hydroxybutanoic acid methyl ester; Methyl (2S,3S)-2-amino-3-hydroxybutanoate; allo-Threonine methyl ester, L-; Methyl L-allothreoninate; H-allo-Thr-OMe; allo-Thr-OMe
EINECS	Contact for details

Quality Control

Our L-Allo-Threoninemethylester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.