Description

(S)-(-)-2-Hydroxy-2'-Methoxy-1,1'-Bi-Naphthol is a high-value, enantiomerically pure chiral ligand and building block of significant importance in asymmetric synthesis. Its core value lies in its ability to induce high stereoselectivity in catalytic reactions, which is critical for producing single-enantiomer compounds in the pharmaceutical and fine chemical industries. This product is essential for research chemists and process development scientists working on the synthesis of chiral drugs, agrochemicals, and advanced materials where precise control of molecular handedness is required.

Application

• As a chiral ligand in asymmetric metal-catalyzed reactions, including additions and couplings.
• As a key resolving agent or chiral auxiliary in the synthesis of enantiomerically pure pharmaceutical intermediates.
• In the development of novel chiral catalysts for academic and industrial research.
• As a building block for the synthesis of complex natural products and specialty chemicals.
• In material science for the creation of chiral polymers or frameworks with specific optical properties.
• For analytical purposes as a chiral selector or standard in chromatography.

Basic Information

Product Name	(S)-(-)-2-Hydroxy-2'-Methoxy-1,1'-Bi-Naphthol
CAS No.	79547-82-3
Molecular Formula	C21H16O3
Molecular Weight	316.35 g/mol
Synonyms	(S)-(-)-2,2'-Dihydroxy-1,1'-binaphthyl-3-methoxy; (S)-3-Methoxy-2,2'-dihydroxy-1,1'-binaphthyl; (S)-(-)-3-Methoxy-BINOL; (S)-Methoxy-BINOL; (S)-2'-Methoxy-2-hydroxy-1,1'-binaphthyl; (S)-(-)-2-Hydroxy-2'-methoxy-1,1'-binaphthyl; (S)-Methoxybinaphthol; (S)-3-MeO-BINOL
EINECS	Contact for details

Quality Control

Our (S)-(-)-2-Hydroxy-2'-Methoxy-1,1'-Bi-Naphthol is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. We provide comprehensive analytical data, including HPLC for chemical purity and chiral HPLC or polarimetry for enantiomeric excess (ee) verification. Certificates of Analysis (COA) detailing all specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C) under an inert atmosphere to prevent oxidation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.