Description

Methyl 4-(4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate is a specialized nitrogen mustard derivative, a chemical class known for its alkylating properties and significant role in advanced synthetic chemistry. This compound matters as a critical pharmaceutical intermediate and a versatile building block for creating complex molecules with targeted biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical sectors, particularly those developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nitrogen mustard-based chemotherapeutic agents and targeted cancer therapies.
• Bioconjugation & Prodrug Development: Serves as a functional handle for attaching targeting ligands or creating inactive prodrug forms that are activated in specific biological environments.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive compounds with alkylating mechanisms.
• Chemical Biology Tool: Used in the development of molecular probes to study DNA alkylation, protein interactions, and cellular pathways.
• Fine Chemical Synthesis: Employed in multi-step organic syntheses requiring the introduction of a bifunctional (amine and ester) aromatic moiety.
• Polymer Modification: Potential use in creating functionalized polymers with specific reactive sites for further chemical elaboration.

Basic Information

Product Name	Methyl 4-(4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate
CAS No.	79481-83-7
Molecular Formula	C15H21Cl2NO2
Molecular Weight	318.24 g/mol
Synonyms	Methyl 4-[4-[Bis(2-chloroethyl)amino]phenyl]butyrate; 4-[4-[Bis(2-chloroethyl)amino]phenyl]butanoic Acid Methyl Ester; Methyl 4-(p-[N,N-Bis(2-chloroethyl)amino]phenyl)butyrate; Phenylbutyric Acid Methyl Ester Nitrogen Mustard Derivative; Chlorambucil Methyl Ester Analog; L-PAM Ester Derivative; NSC 75766 (related); Butanoic acid, 4-[4-[bis(2-chloroethyl)amino]phenyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4-(4-(Bis(2-Chloroethyl)Amino)Phenyl)Butyrate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support GMP-guided applications where traceability and consistency are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Handle and store in accordance with all applicable local and international regulations for reactive chemical intermediates.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.