Description

2-Amino-5-Bromo-3-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block distinguished by its bromine and trifluoromethyl substituents. This compound is critical for medicinal chemistry and advanced materials research, enabling the synthesis of complex molecules with tailored biological and physical properties. It is primarily sought after by pharmaceutical R&D teams, agrochemical innovators, and specialty chemical manufacturers for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or fluorinated polymers, due to its electron-deficient pyridine core.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, photoaffinity labels, and other molecular probes to study biological systems.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis services catering to the fine chemical and life science industries.

Basic Information

Product Name	2-Amino-5-Bromo-3-(Trifluoromethyl)Pyridine
CAS No.	79456-34-1
Molecular Formula	C6H4BrF3N2
Molecular Weight	241.01 g/mol
Synonyms	5-Bromo-3-(trifluoromethyl)pyridin-2-amine; 2-Amino-5-bromo-3-trifluoromethylpyridine; 5-Bromo-3-trifluoromethyl-2-pyridinamine; 2-Pyridinamine, 5-bromo-3-(trifluoromethyl)-; 5-Bromo-3-(trifluoromethyl)-2-aminopyridine; 2-Amino-5-bromo-α,α,α-trifluoro-3-picoline
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Bromo-3-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.