Description

2-Amino-3-Bromo-5-(Trifluoromethyl)-Pyridine is a high-purity, multi-functional heterocyclic building block of significant commercial and research interest. Its molecular structure, featuring amino, bromo, and trifluoromethyl substituents on a pyridine core, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by pharmaceutical, agrochemical, and advanced materials research sectors for applications in drug discovery, crop protection, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in the synthesis of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl groups.
• Material Science Research: Serves as a precursor for functionalized ligands in catalysis and for creating advanced organic frameworks and electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for designing molecular probes, tags, and linkers used in bioconjugation and target identification studies.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-Amino-3-Bromo-5-(Trifluoromethyl)-Pyridine
CAS No.	79456-30-7
Molecular Formula	C6H4BrF3N2
Molecular Weight	241.01 g/mol
Synonyms	3-Bromo-2-amino-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-bromopyridin-2-amine; 2-Pyridinamine, 3-bromo-5-(trifluoromethyl)-; 3-Bromo-5-trifluoromethylpyridin-2-ylamine; 2-Amino-3-bromo-5-trifluoromethylpyridine; 3-Bromo-2-amino-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Bromo-5-(Trifluoromethyl)-Pyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.