Description

2,4-Octadienoic Acid, 7-(T-Butyldimethylsilyloxy)-, Methyl Ester (E,E) is a high-purity, protected synthetic intermediate of significant value in advanced organic synthesis. This compound is specifically engineered to provide a stable, reactive handle for the controlled introduction of the 2,4-octadienoate moiety in complex molecular architectures. It is an essential building block for researchers and process chemists in the pharmaceutical and agrochemical industries, enabling the synthesis of novel active ingredients and fine chemicals. The (E,E) stereochemistry ensures precise structural control, which is critical for achieving desired biological activity and material properties.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of complex drug candidates, particularly those requiring stereochemically defined diene systems.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides where the dienoate structure is a core pharmacophore.
• Fine Chemical Production: Serves as a versatile precursor for the manufacture of specialty chemicals, flavors, and fragrances requiring specific unsaturated ester functionalities.
• Material Science Research: Employed in the development of advanced polymers and functional materials that incorporate controlled unsaturation for cross-linking or property modification.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry, including studies on silyl protection/deprotection strategies and cross-coupling reactions.

Basic Information

Product Name	2,4-Octadienoic Acid, 7-(T-Butyldimethylsilyloxy)-, Methyl Ester (E,E)
CAS No.	79427-02-4
Molecular Formula	C₁₅H₂₈O₃Si
Molecular Weight	284.47 g/mol
Synonyms	Methyl (2E,4E)-7-[(tert-Butyldimethylsilyl)oxy]-2,4-octadienoate; Methyl 7-(tert-Butyldimethylsiloxy)-2,4-octadienoate; (E,E)-Methyl 7-(TBDMSO)-2,4-octadienoate; 7-TBDMSO-2,4-octadienoic acid methyl ester; TBDMS-protected methyl octadienoate; 79427-02-4; Methyl (E,E)-7-((tert-butyldimethylsilyl)oxy)octa-2,4-dienoate
EINECS	Contact for details

Quality Control

Our 2,4-Octadienoic Acid, 7-(T-Butyldimethylsilyloxy)-, Methyl Ester (E,E) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment supports compliance with cGMP guidelines for advanced pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E,E)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.