Description

4-(1,4-Dioxa-8-Azaspiro[4.5]Decan-8-Yl)Benzonitrile is a high-value, nitrogen-containing heterocyclic building block featuring a spirocyclic acetal-protected amine and a benzonitrile moiety. This compound is specifically engineered to serve as a critical intermediate in advanced organic synthesis, offering a protected functional handle for constructing complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex heterocycles.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its spirocyclic structure can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of advanced organic materials, such as organic semiconductors or specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	4-(1,4-Dioxa-8-Azaspiro[4.5]Decan-8-Yl)Benzonitrile
CAS No.	79421-39-9
Molecular Formula	C16H18N2O2
Molecular Weight	270.33 g/mol
Synonyms	4-(1,4-Dioxa-8-azaspiro[4.5]dec-8-yl)benzonitrile; 8-(4-Cyanophenyl)-1,4-dioxa-8-azaspiro[4.5]decane; 4-(1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)benzonitrile; 4-(1,4-Dioxa-8-azaspiro[4.5]decyl)benzonitrile; 4-(8-Aza-1,4-dioxaspiro[4.5]decan-8-yl)benzonitrile; 4-(1,4-Dioxa-8-azaspiro[4.5]decan-8-yl)phenyl cyanide; Spirocyclic Acetal Protected Aminobenzonitrile; CAS 79421-39-9
EINECS	Contact for details

Quality Control

Every batch of 4-(1,4-Dioxa-8-Azaspiro[4.5]Decan-8-Yl)Benzonitrile is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.