Description

Trimethylsilyl 3,5-Bis(Trimethylsilyloxy)Benzoate is a specialized organosilicon derivative of benzoic acid, featuring multiple trimethylsilyl protecting groups. This compound is valued for its role as a key synthetic intermediate and protecting group reagent in advanced organic synthesis, particularly for sensitive or complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a protected benzoic acid derivative in the multi-step synthesis of complex drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides and fungicides where the protected phenolic and carboxylic acid functionalities are required.
• Polymer & Material Science: Acts as a monomer or modifying agent in the production of specialty silicones and high-performance polymers with tailored thermal and surface properties.
• Organic Synthesis Reagent: Functions as a versatile protecting group for dihydroxybenzoic acids, enabling selective reactions in complex molecular architectures.
• Liquid Crystal & OLED Materials: Employed in the research and development of advanced electronic display materials and organic semiconductors.
• Cosmetic & Personal Care Ingredients: Potential intermediate for UV absorbers or stabilizers in high-end sunscreen and skincare formulations.

Basic Information

Item	Detail
Product Name	Trimethylsilyl 3,5-Bis(Trimethylsilyloxy)Benzoate
CAS No.	79314-27-5
Molecular Formula	C18H34O4Si3
Molecular Weight	398.71 g/mol
Synonyms	3,5-Bis(trimethylsiloxy)benzoic acid trimethylsilyl ester; Benzoic acid, 3,5-bis[(trimethylsilyl)oxy]-, trimethylsilyl ester; TMS-3,5-bis(TMS-oxy)benzoate; Trimethylsilyl 3,5-di-O-(trimethylsilyl)salicylate (common misnomer); 3,5-Bis-O-(trimethylsilyl)salicylic acid TMS ester; TMS-protected 3,5-dihydroxybenzoate
EINECS	Contact for details

Quality Control

Our Trimethylsilyl 3,5-Bis(Trimethylsilyloxy)Benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation by NMR and IR spectroscopy. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when opening to prevent decomposition. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.