Description

8-Azidoadenine is a versatile adenine derivative where an azido group replaces a hydrogen atom, creating a valuable biochemical building block. This functionalization makes it a critical intermediate for synthesizing nucleoside analogs, click chemistry probes, and other modified biomolecules. It is essential for researchers and manufacturers in pharmaceutical development, life science research, and the production of advanced diagnostic reagents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Bioconjugation & Click Chemistry: Acts as a reactive handle for Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) to label biomolecules like DNA, RNA, and proteins.
• Proteomics & Chemical Biology: Used to create activity-based probes (ABPs) for studying enzyme function and metabolic pathways.
• Nucleic Acid Research: Incorporation into oligonucleotides to study structure-function relationships or to create cross-linking agents.
• Material Science: Functionalization agent for creating bio-hybrid materials and surfaces with specific biological recognition properties.
• Diagnostic Reagent Development: Building block for fluorescent or affinity tags used in assay and sensor development.

Basic Information

Product Name	8-Azidoadenine
CAS No.	79270-98-7
Molecular Formula	C5H4N8
Molecular Weight	176.14 g/mol
Synonyms	8-Azido-9H-purine-6-amine; 8-Azidoadenine; 6-Amino-8-azidopurine; 8-Azidoadenine; Adenine, 8-azido-; 8-N3-Ade
EINECS	Contact for details

Quality Control

Our 8-Azidoadenine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopy (NMR, IR). We provide full traceability and a Certificate of Analysis (COA) with every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive nature, prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.