Description

6'-Bromospiro[Cyclopentane-1,3'-Indolin]-2'-One is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic indolinone scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis.
• Kinase Inhibitor Development: Employed in the synthesis of potential kinase inhibitors due to its privileged heterocyclic structure.
• Chemical Biology Probes: Serves as a starting material for creating chemical probes to study biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and methodology development.

Basic Information

Product Name	6'-Bromospiro[Cyclopentane-1,3'-Indolin]-2'-One
CAS No.	79208-84-7
Molecular Formula	C₁₂H₁₂BrNO
Molecular Weight	266.14 g/mol
Synonyms	6'-Bromo-1'H-spiro[cyclopentane-1,3'-indol]-2'(2'H)-one; 6'-Bromospiro[cyclopentane-1,3'-indolin]-2'-one; 2H-Indol-2-one, 1,3-dihydro-6'-bromospiro[cyclopentane-1,3'-[3H]indol]-2'-one; Spiro[cyclopentane-1,3'-indolin]-2'-one, 6'-bromo-; 6-Bromospiro[cyclopentane-1,3'-indolin]-2'-one
EINECS	Contact for details

Quality Control

Our 6'-Bromospiro[Cyclopentane-1,3'-Indolin]-2'-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications. Our quality commitment supports applications in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.