Description

(E)-4-(Methylthio)Chalcone is a high-purity, synthetic organic compound belonging to the chalcone class, characterized by its distinct (E)-configuration and a methylthio substituent. This compound serves as a versatile and valuable chemical intermediate and research chemical for advanced organic synthesis and material science applications. It is primarily utilized by R&D laboratories and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting inflammation, cancer, and microbial infections.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its chalcone backbone for bioactive molecule design.
• Organic Synthesis: Acts as a precursor for heterocyclic compounds and complex molecular architectures via reactions like cyclization and functional group transformations.
• Material Science: Investigated for use in organic semiconductors, non-linear optical (NLO) materials, and as a monomer for specialized polymers.
• Biochemical Research: Employed as a standard or probe in studies related to enzyme inhibition, antioxidant activity, and structure-activity relationships (SAR).
• Flavor & Fragrance Industry: Potential use as an intermediate for synthesizing specific aroma chemicals, given the chalcone structural motif.

Basic Information

Product Name	(E)-4-(Methylthio)Chalcone
CAS No.	79134-84-2
Molecular Formula	C₁₆H₁₄OS
Molecular Weight	254.35 g/mol
Synonyms	(E)-1-(4-(Methylthio)phenyl)-3-phenylprop-2-en-1-one; 4-Methylmercaptochalcone; 4-(Methylthio)chalcone; (E)-4-Methylthiochalcone; 3-Phenyl-1-[4-(methylthio)phenyl]-2-propen-1-one; 1-[4-(Methylsulfanyl)phenyl]-3-phenylprop-2-en-1-one; p-(Methylthio)chalcone
EINECS	Contact for details

Quality Control

Our (E)-4-(Methylthio)Chalcone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	98 - 102 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.