Description

tert-Butyl 4-(2-Aminophenylamino)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders. It is essential for R&D chemists and process development scientists in the pharmaceutical and fine chemical industries who require reliable, high-quality intermediates for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• API Synthesis: Used in the multi-step manufacturing of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of target molecules.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	tert-Butyl 4-(2-Aminophenylamino)Piperidine-1-Carboxylate
CAS No.	79099-00-6
Molecular Formula	C16H25N3O2
Molecular Weight	291.39 g/mol
Synonyms	1-Boc-4-[(2-aminophenyl)amino]piperidine; 1-(tert-Butoxycarbonyl)-4-[(2-aminophenyl)amino]piperidine; 4-[(2-Aminophenyl)amino]-1-piperidinecarboxylic acid 1,1-dimethylethyl ester; tert-Butyl 4-[(2-aminophenyl)amino]-1-piperidinecarboxylate; N-Boc-4-(2-aminophenylamino)piperidine; 79099-00-6; 4-(2-Aminophenylamino)piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Aminophenylamino)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.