Description

Cyclobutanecarboxylic Acid, 2-Ethenyl-, Methyl Ester, (1R-Trans)- (9Ci) is a specialized chiral ester building block of significant interest in advanced organic synthesis. Its unique cyclobutane ring fused with a vinyl group offers a constrained, three-dimensional scaffold that is highly valuable for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring rigid, sterically defined frameworks.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the cyclobutane structure can influence biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science: Investigated as a monomer or cross-linking agent for producing polymers with unique thermal and mechanical properties.
• Fragrance and Flavor Chemistry: Potential use in synthesizing novel aroma chemicals due to its volatile ester nature and complex structure.
• Academic and R&D: Fundamental research tool in organic chemistry for studying ring strain, stereochemistry, and novel reaction pathways.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 2-Ethenyl-, Methyl Ester, (1R-Trans)- (9Ci)
CAS No.	79091-92-2
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	(1R,2S)-2-Vinylcyclobutanecarboxylic acid methyl ester; Methyl (1R,2S)-2-vinylcyclobutanecarboxylate; trans-2-Vinylcyclobutanecarboxylic acid methyl ester; (1R-trans)-2-Ethenylcyclobutanecarboxylic Acid Methyl Ester; 2-Vinylcyclobutanecarboxylic acid methyl ester, (1R,2S)-; Methyl trans-2-vinylcyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Every batch of Cyclobutanecarboxylic Acid, 2-Ethenyl-, Methyl Ester, (1R-Trans)- (9Ci) is produced and analyzed under strict quality management protocols to ensure high chemical and enantiomeric purity. Our quality assurance includes comprehensive analytical testing via HPLC, GC, Chiral HPLC, and NMR to confirm identity, purity, and isomeric composition. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its highly volatile nature, keep containers tightly sealed when not in use and away from heat, sparks, and open flames. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.