Description

(R)-3,4-Di-o-Pivaloylepinephrine Hydrochloride is a high-purity chiral intermediate and a protected derivative of epinephrine. This compound matters for its critical role in the synthesis of enantiomerically pure pharmaceuticals and advanced research chemicals, where stereochemical integrity is paramount. It is primarily needed by pharmaceutical R&D teams, process chemists, and fine chemical manufacturers developing or producing adrenergic agents, chiral catalysts, and other specialized organic molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of chiral β-adrenergic receptor agonists and antagonists.
• Asymmetric Synthesis: Used as a chiral precursor or auxiliary in the preparation of enantiomerically pure compounds.
• Biochemical Research: Valuable tool for studying adrenergic pathways, receptor binding, and signal transduction mechanisms.
• Process Chemistry: Serves as a protected form of epinephrine for multi-step synthetic routes in API (Active Pharmaceutical Ingredient) development.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Fine Chemical Production: Intermediate for the manufacture of specialized chemicals used in advanced material science and diagnostics.

Basic Information

Product Name	(R)-3,4-Di-o-Pivaloylepinephrine Hydrochloride
CAS No.	79071-01-5
Molecular Formula	C₁₉H₂₉NO₅·HCl
Molecular Weight	403.90 g/mol
Synonyms	(R)-3,4-Di-O-pivaloyl-epinephrine hydrochloride; (R)-(-)-3,4-Di-O-pivaloylepinephrine HCl; L-Epinephrine 3,4-di-pivalate hydrochloride; (R)-Adrenaline 3,4-dipivalate hydrochloride; 1-[(3,4-Bis(2,2-dimethylpropanoyloxy)phenyl]-2-(methylamino)ethanol hydrochloride; (R)-1-(3,4-Bis(pivaloyloxy)phenyl)-2-(methylamino)ethanol hydrochloride; (R)-3',4'-Di-O-pivaloylepinephrine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-3,4-Di-o-Pivaloylepinephrine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.