Description

3-Bromo-4-Trimethylsilanyl-1H-Pyrazole is a high-value organosilicon-substituted pyrazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both a bromine substituent and a trimethylsilyl protecting group, makes it a versatile building block for constructing complex heterocyclic systems. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Precursor: Employed in the creation of specialized polymers, ligands for catalysis, and advanced organic electronic materials.
• Chemical Synthesis Reagent: Acts as a versatile reactant for introducing functionalized pyrazole motifs into more complex molecular architectures via cross-coupling and other metal-catalyzed reactions.
• Academic & Contract Research: Essential for methodological development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-Bromo-4-Trimethylsilanyl-1H-Pyrazole
CAS No.	78907-82-1
Molecular Formula	C7H13BrN2Si
Molecular Weight	233.18 g/mol
Synonyms	3-Bromo-4-(trimethylsilyl)-1H-pyrazole; 4-Trimethylsilyl-3-bromo-1H-pyrazole; 1H-Pyrazole, 3-bromo-4-(trimethylsilyl)-; 3-Bromo-4-trimethylsilylpyrazole; 78907-82-1; 3-Bromo-4-TMS-1H-pyrazole; 4-(Trimethylsilyl)-3-bromo-1H-pyrazole
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-Trimethylsilanyl-1H-Pyrazole is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical research and production needs. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.