Description

1-Phenyl-2-Trimethylsilylacetylene is a versatile organosilicon building block featuring both a phenyl group and a protected terminal alkyne. This compound is valued for its role as a key synthetic intermediate in advanced organic and medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing arylacetylene motifs.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that require specific silicon-containing alkyne structures.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of advanced polymers, resins, and silicon-based hybrid materials.
• Organic Synthesis Reagent: Employed in Sonogashira coupling and other cross-coupling reactions to introduce phenylacetylene units into target molecules.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for transition metal catalysis and organometallic chemistry.
• Chemical Research: A fundamental reagent in academic and industrial R&D for exploring new synthetic methodologies and reaction pathways.

Basic Information

Product Name	1-Phenyl-2-Trimethylsilylacetylene
CAS No.	78905-09-6
Molecular Formula	C11H14Si
Molecular Weight	174.31 g/mol
Synonyms	((Trimethylsilyl)ethynyl)benzene; Ethynyltrimethylsilane, phenyl-; Phenyl(trimethylsilyl)acetylene; Trimethyl(phenylethynyl)silane; Phenylethynyltrimethylsilane; TMS-Phenylacetylene; 1-Trimethylsilyl-2-phenylethyne; Benzene, [(trimethylsilyl)ethynyl]-
EINECS	Contact for details

Quality Control

Our 1-Phenyl-2-Trimethylsilylacetylene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.