Description

Isovaline, 2-Hydroxy-, Ethyl Ester is a specialized chiral building block and ester derivative of the non-proteinogenic amino acid isovaline. This compound matters for its utility in advanced organic synthesis, particularly in the construction of complex molecules where stereochemistry and specific functional groups are critical. It is needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications ranging from medicinal chemistry to the synthesis of novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and metabolic targets.
• Agrochemical Synthesis: Used in the preparation of novel herbicides, fungicides, and plant growth regulators that require specific stereochemical configurations for optimal activity.
• Peptidomimetics & Bioactive Molecule Design: Acts as a constrained amino acid analog for creating peptide mimics with enhanced metabolic stability and binding affinity.
• Ligand & Catalyst Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: A valuable precursor for manufacturing specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: Utilized as a standard or reagent in methodological studies and for probing biochemical pathways.

Basic Information

Product Name	Isovaline, 2-Hydroxy-, Ethyl Ester
CAS No.	78843-73-9
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	Ethyl 2-hydroxy-3-methylbutanoate; 2-Hydroxy-3-methylbutyric acid ethyl ester; Ethyl 2-hydroxyisovalerate; Ethyl 2-hydroxy-3-methylbutyrate; 3-Methyl-2-hydroxybutyric acid ethyl ester; (±)-Ethyl 2-hydroxy-3-methylbutanoate; DL-Ethyl 2-hydroxy-3-methylbutyrate
EINECS	Contact for details

Quality Control

Our Isovaline, 2-Hydroxy-, Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (if applicable), and impurity profiles are available upon request to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Purity (Chiral HPLC)	Specify required enantiomeric excess (ee)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.