Description

2-Amino-2-Methyl-3-Hydroxy-Propanoic Acid Ethyl Ester is a specialized amino acid derivative that serves as a versatile chiral building block in advanced organic synthesis. Its unique structure, featuring both amino and hydroxyl functional groups, makes it a critical intermediate for constructing complex molecules with high stereochemical purity. This compound is essential for research and production in the pharmaceutical and fine chemical industries, where it is used to develop active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel APIs, particularly in therapeutic areas requiring specific stereochemistry.
• Peptide Mimetics & Modifications: Used to introduce non-natural amino acid residues into peptide chains to enhance stability, bioavailability, or biological activity.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions to produce enantiomerically pure compounds.
• Ligand & Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in stereoselective transformations.
• Bioconjugation & Probe Synthesis: Utilized in the development of biochemical probes and labeled compounds for diagnostic and research applications.
• Fine Chemical Production: A building block for synthesizing specialty chemicals, flavors, and fragrances that require precise molecular architecture.

Basic Information

Product Name	2-Amino-2-Methyl-3-Hydroxy-Propanoic Acid Ethyl Ester
CAS No.	78843-72-8
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	Ethyl 2-Amino-2-Methyl-3-Hydroxypropanoate; 3-Hydroxy-2-(aminomethyl)-2-methylpropanoic Acid Ethyl Ester; 2-Amino-2-methyl-3-hydroxypropionic Acid Ethyl Ester; 2-(Aminomethyl)-2-methyl-3-hydroxypropanoic Acid Ethyl Ester; Ethyl 3-Hydroxy-2-(aminomethyl)-2-methylpropionate; 2-Methylserine Ethyl Ester; Amino Methyl Hydroxy Methyl Propionate Ethyl Ester
EINECS	Contact for details

Quality Control

Our 2-Amino-2-Methyl-3-Hydroxy-Propanoic Acid Ethyl Ester is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and research applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.