Description

α-[2-[Bis(Isopropyl)Amino]Ethyl]-α-Isobutylpyridine-2-Acetonitrile is a specialized organic compound featuring a pyridine-acetonitrile core functionalized with a branched alkyl and a tertiary aminoethyl side chain. This unique molecular architecture makes it a valuable high-purity intermediate for the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought by research and development chemists and process scale-up teams in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological or cardiovascular pathways.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides due to its nitrogen-containing heterocyclic structure.
• Ligand Precursor: Serves as a starting material for the preparation of complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new chemical entities and reaction methodologies.
• Custom Synthesis: A critical substrate for contract research and manufacturing organizations (CROs/CMOs) offering bespoke chemical synthesis services.

Basic Information

Product Name	α-[2-[Bis(Isopropyl)Amino]Ethyl]-α-Isobutylpyridine-2-Acetonitrile
CAS No.	78833-05-3
Molecular Formula	C19H31N3
Molecular Weight	301.47 g/mol
Synonyms	2-[(2-{Bis[(propan-2-yl)amino]ethyl})(2-methylpropyl)amino]-2-pyridin-2-ylacetonitrile; α-Isobutyl-α-[2-[bis(1-methylethyl)amino]ethyl]-2-pyridineacetonitrile; 2-Pyridineacetonitrile, α-[2-[bis(1-methylethyl)amino]ethyl]-α-(2-methylpropyl)-; (2-Pyridyl)(isobutyl)(2-diisopropylaminoethyl)acetonitrile; 78833-05-3; UNII-8V4V5WY9WQ
EINECS	Contact for details

Quality Control

Our α-[2-[Bis(Isopropyl)Amino]Ethyl]-α-Isobutylpyridine-2-Acetonitrile is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects requiring material that meets ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.