Description

α-Isobutylpyridine-2-Acetonitrile is a versatile pyridine-based nitrile compound, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it a valuable precursor for the development of complex heterocyclic systems and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing pyridine or nicotinonitrile moieties.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Functional Material Research: Employed in the research and development of organic electronic materials and liquid crystals.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis Projects: A fundamental building block for contract research organizations (CROs) and CDMOs engaged in custom chemical synthesis.

Basic Information

Product Name	α-Isobutylpyridine-2-Acetonitrile
CAS No.	78833-04-2
Molecular Formula	C11H14N2
Molecular Weight	174.25 g/mol
Synonyms	2-(2-Isobutylpyridin-4-yl)acetonitrile; 4-(Cyanomethyl)-2-isobutylpyridine; 2-Isobutyl-4-pyridineacetonitrile; α-(2-Isobutyl-4-pyridyl)acetonitrile; (2-Isobutylpyridin-4-yl)acetonitrile; Pyridine, 2-(2-methylpropyl)-4-(cyanomethyl)-; 78833-04-2
EINECS	Contact for details

Quality Control

Our α-Isobutylpyridine-2-Acetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.